Eosinophil production and function are influenced by a cytokine called interleukin-5 (IL-5).4 Fasenra is a monoclonal antibody active agai… Side Effects What are the side effects of Benralizumab (Fasenra Pen)?. It is used in addition to other medication to treat the symptoms of a type of asthma called eosinophilic asthma. When inappropriately activated, however, eosinophils can damage tissues and result in asthma. Headache may occur. Ask your doctor or pharmacist for more information. Applies to benralizumab: subcutaneous solution. How should I store FASENRA? Before you receive benralizumab, tell your doctor about all your medical conditions or allergies , all medicines you use, and if you are pregnant or breast -feeding. Although not all of these side effects may occur, if they do occur they may need medical attention. What should I know regarding pregnancy, nursing and administering Fasenra Syringe to children or the elderly? WebMD does not provide medical advice, diagnosis or treatment. You may report them to the FDA. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. How Much Do You Know About Adult Whooping Cough? Common side effects may include: sore throat; or; headache. It comes as a syringe and an autoinjector pen. Some side effects may not be reported. These are not all the possible side effects of FASENRA. Please contact your doctor or pharmacist. Fasenra Side Effects See also How to Use section. FASENRA is designed to target cells in your body called eosinophils, which can be a key cause of severe asthma. Store FASENRA in the refrigerator between 36°F to 46°F (2°C to 8°C). Side effects requiring immediate medical attention. This medication may be used when other "preventer" asthma medications, such as long-acting bronchodilators and corticosteroids have not been effective. Selected from data included with permission and copyrighted by First Databank, Inc. The most common side effects of FASENRA include: headache and sore throat. FASENRA Side Effects by Likelihood and Severity . Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Fasenra Pen Side Effects See also How to Use section. APPROVED USE. Fasenra (benralizumab) injection is an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody (IgG1, kappa) indicated for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype.. What Are Side Effects of Fasenra? Things to remember when you fill your prescription. for asthma. COMMON side effects ... RARE side effects If experienced, these tend to have a Severe expression i . Call your doctor for medical advice about side effects. Side effects of Dupixent and Fasenra that are similar include injection site reactions (pain, redness, itching, or a small lump). What is Fasenra used for and how does it work? This survey is being conducted by the WebMD marketing sciences department. What type of asthma is Fasenra used to treat? decreased function of the adrenal gland ; Common side effects of Fasenra include: We comply with the HONcode standard for trustworthy health information -. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Frequency not reported: Anaphylaxis, angioedema[Ref], Frequency not reported: Immunogenicity[Ref], Common (1% to 10%): Injection site reactions (e.g., pain, erythema, pruritus, papule)[Ref], Common (1% to 10%): Pharyngitis (bacterial, viral, or streptococcal), cough[Ref]. You may report side effects to the FDA at 1-800-FDA-1088. Headache may occur. Portions of this document last updated: Feb. 01, 2021 Below are examples of these side effects. 1. Common Fasenra side effects may include: sore throat; or. You may report side effects to FDA at 1-800-FDA-1088. Side Effects for FASENRA (benralizumab injection, solution) are also known as adverse reactions. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Last updated on June 8, 2020. You may report side effects to FDA at 1-800-FDA-1088. These side effects may go away during treatment as your body adjusts to the medicine. Learn about side effects, dosage, alternatives, and more. Other side effects not listed may also occur in some patients. SIROCCO and CALIMA (Trials 1 and 2) SIROCCO (48-week) and CALIMA (56-week) were 2 randomized, double-blind, parallel-group, placebo-controlled, multicenter studies comparing FASENRA 30 mg SC Q4W for the first 3 doses, then Q8W thereafter; benralizumab 30 mg SC Q4W, and placebo SC. Some of the dosage forms listed on this page may not apply to the brand name Fasenra. Please read Patient Information and Prescribing Information for FASENRA. For Asthma: “I received my first Fasenra shot one month ago. If you notice any other effects, check with your healthcare professional. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Fasenra (benralizumab)." Call your doctor for medical advice about side effects. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The most common side effects of FASENRA include headache and sore throat. If this effect lasts or gets worse, tell your doctor or pharmacist promptly. Nucala and Fasenra can cause some similar side effects and some different side effects. © 2005 - 2021 WebMD LLC. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. asthma with elevated level of eosinophils, polyps of the lining of the uterus or the endometrium, a significant type of allergic reaction called anaphylaxis, a type of allergic reaction called angioedema, inflammation of the tissue lining the sinuses. Available for Android and iOS devices. swelling of the eyelids, face, lips, hands, or feet, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. Both Fasenra and Nucala may interact with other drugs. "Product Information. These are not all the possible side effects of FASENRA. Call your doctor for medical advice about side effects. The safety information above does not replace discussions with your healthcare provider about your medical condition or treatment. More common side effects. Fasenra is administered as a shot under the skin. As is the case with all medications, Fasenra can cause side effects which may be mild or severe 6. headache. Along with its needed effects, benralizumab (the active ingredient contained in Fasenra) may cause some unwanted effects. What is the most important information I should know about benralizumab (Fasenra Pen, Fasenra Prefilled Syringe)? These are not all the possible side effects of FASENRA. The most common side effects with Cinqair are: Sore throat; Muscle aches; Severe allergic reactions (rare) Fasenra® (benralizumab) Fasenra is a medication for patients with eosinophilic asthma and works by reducing the number of eosinophils in your blood. Fasenra : Uses, Side Effects, Interactions & More Fasenra (Benralizumab) injection is used together with other medications to prevent wheezing, shortness of breath, chest tightness, and cough caused by asthma in adults and children 12 years of age and older whose asthma is not controlled by their current medication. All rights reserved. To understand how Fasenra works, it’s important to examine the relationship between eosinophils, a type of white blood cell, and asthma. Side effects of Fasenra that are different from Nucala include sore throat, fever, and hypersensitivity reactions. This is not a complete list of Fasenra side effects. What is the most important information I should know about benralizumab (Fasenra Pen, Fasenra Prefilled Syringe)? Typically, eosinophils protect us against parasitic worms. Fasenra may be injected by a healthcare professional, or by the patient once training has been provided. The most common side effects of FASENRA include: headache and sore throat. Medically reviewed by Drugs.com. Call your doctor for medical advice about side effects. APPROVED USE. Sorry, we have no data available. The most common side effects of FASENRA include: headache and sore throat. This is not a complete list of side effects and others may occur. Side effects of Nucala that are different from Fasenra include back pain, fatigue, flu symptoms, urinary tract infection , abdominal pain, itching, eczema, and muscle spasms. Astra-Zeneca Pharmaceuticals, Wilmington, DE. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Fasenra received an overall rating of 6 out of 10 stars from 6 reviews. You may report side effects to FDA at 1-800-FDA-1088. These are not all the possible side effects of FASENRA. Side effects that you should report to your doctor or health care professional as soon as possible: Allergic Reactions Like Skin Rash, Itching Or Hives, Swelling Of The Face, Lips, Or … However, I was so exhausted from coughing 24/7 and shortness of breath that I finally tried it out of desperation. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. You may report side effects to the FDA at 1-800-FDA-1088. Find patient medical information for Fasenra subcutaneous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Specifically, it is an interleukin-5 inhibitor. On this page about Fasenra you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Common side effects of taking Fasenra include: Headache; Sore throat; Fever These are not all the possible side effects of FASENRA. Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps. Along with its needed effects, benralizumab (the active ingredient contained in Fasenra) may cause some unwanted effects. Data sources include IBM Watson Micromedex (updated 3 Mar 2021), Cerner Multum™ (updated 1 Mar 2021), ASHP (updated 3 Mar 2021) and others. Fasenra Side Effects & Safety. I was reluctant to take injections because of the possible side effects, especially parasites. Select a condition to view a list of medication options. If this effect lasts or gets worse, tell your doctor or pharmacist promptly. What Is Fasenra? The benefit and side effects of FASENRA were evaluated in three clinical trials of patients with severe asthma and increased eosinophilic white cells in blood. Check with your doctor immediately if any of the following side effects occur while taking benralizumab: Some side effects of benralizumab may occur that usually do not need medical attention. IMPORTANT SAFETY INFORMATION FASENRA is a prescription medicine used with other asthma medicines for the maintenance treatment of asthma in people Note: This document contains side effect information about benralizumab. Fasenra (benralizumab) is a brand-name drug used for severe eosinophilic asthma. Get emergency medical help if you have signs of an allergic reaction to Fasenra: hives, rash; difficult breathing, feeling light-headed; swelling of your face, lips, tongue, or throat. What conditions does Fasenra Syringe treat? Tell your doctor if you have any side effects that bother you or that do not go away. Call your doctor at once if you have: new or worsening asthma symptoms. See what others have said about Fasenra, including the effectiveness, ease of use and side effects. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. prednisone, Breo Ellipta, Xopenex, Dulera, Atrovent, Nucala. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter. So so glad I did. Read more about FASENRA for severe asthma, dosing, side effects, risks and how FASENRA … Although not all of these side effects may occur, if they do occur they may need medical attention. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Fasenra is indicated for the add-on maintenance treatment of patients with severe asthma aged 12 years and older, and with an eosinophilic phenotype [see Clinical Studies (14)].Limitations of use: Fasenra: Benralizumab belongs to the class of medications called monoclonal antibodies. Fasenra side effects. Below is a summary of known side effects for FASENRA. The most common side effects of FASENRA include: headache and sore throat.